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The influenza virus causes one of the
world's most serious respiratory illnesses. It is potentially fatal
and infects humans in the tens of millions each year.
What is Influenza?
Influenza is a viral infection of the
respiratory tract. Influenza viruses are often divided into three
types: A, B and C. Type A is a constantly changing virus that is
generally responsible for the large outbreaks. New strains of Type A
virus develop regularly, with outbreaks occurring in most years.
Type B outbreaks occur at intervals of several years, while Type C
is considered relatively insignificant.
How is it Spread?
Influenza virus in humans is spread
from infected people through coughing and sneezing. These viruses
contaminate the air, hands and surfaces of our environment. The
incubation period is very short (from 1 to 4 days) and 15% to 40% of
the population can become infected in a year.
Sick people "shed" the virus and are
contagious for about a week. Immuno-compromised people (cancer,
AIDS, transplant, immune suppressed) can easily contract influenza
and shed the virus for 2-3 weeks, due to their weakened immune
system.
School age children are usually the
first to become ill in each community and are the primary source of
contagion since they shed for 7 to 10 days. With little or no
exposure to influenza, children have less immunity and tend to
experience more severe forms of the flu.
Symptoms
- Fever. Over 37.8 C for 3-5
days. Fever is generally higher in the afternoons and evenings,
with some decrease in the mornings. Fever typically runs higher in
children and can be over 40 C.
- Cough. A major symptom of
influenza, the cough starts as dry and hacking and progresses by
the third day to wet with thick mucous. It can worsen for the next
4 to 7 days and last for over 2 weeks. Children's cough can be
croupy and serious. Smokers are at risk for significant bronchitis
and pneumonia.
- Headaches and myalgia
(muscle aches) can be severe for the first few days and slowly
improve.
- Fatigue. Common and severe,
lasting for 1 to 3 days.
- Sore throat. Most common in
older children and adults. It can be severe for the first few
days.
- Red eyes. Can last for 3 to
4 days and
- Nasal congestion. Can last
for 1 to 2 weeks.
Prevention
Much of the illness and death caused
by influenza can be prevented by annual influenza vaccination (flu
shot). The vaccine must be given every year and is specifically
recommended for people at high risk for developing serious
complications as a result of influenza infection, including:
- All people aged 65 years and older
- People of any age with chronic
diseases of the heart, lung, or kidneys, diabetes, immunosuppression
(AIDS, cancer), or severe forms of anemia.
- Residents of long term care
facilities housing persons with chronic medical conditions.
- Children and teenagers receiving
long term aspiring therapy and who may be at risk for developing
Reye's syndrome.
The influenza vaccine is also
recommended for people in close or frequent contact with anyone in
the high risk groups defined above, including healthcare personnel,
volunteers who work with high risk patients, and people who live in
a household with a high-risk person.
Influenza and bacterial infections
may weaken the body, leaving the body open to other complications,
such as bacterial pneumonia. High risk people should also receive
the pneumonia vaccine.
Other steps for avoiding influenza
include common sense actions such as frequent hand washing,
particularly before cooking and after blowing your nose. This also
helps prevent spreading the flu to other people.
General Treatment
- Give only non-aspirin medicines
such as acetaminophen (Tylenol) for fever, muscles aches and
headaches.
- Drink plenty of fluids to prevent
secretions from getting thick, which can intensify breathing
problems.
- Rest to help your body fight the
infection.
- Antiviral medicines can be used.
- Antibiotics are absolutely not
useful for preventing or treating influenza. They are only used
for bacterial complications after the initial phase is over.
Antiviral Treatments.
An exciting new class of drugs is
just now becoming available for the treatment of influenza. These
drugs, called neuraminidase inhibitors, help stop influenza
virus replication and are active against Influenza Types A and B.
Zanamivir (Relenza), for inhalation, was the first of these new
drugs to be approved. It has been shown to shorten the duration of
flu symptoms if given within 48 hours of symptom onset. Relenza is
administered with the help of a special inhaler and is approved for
use in people 12 years of age and older. Another drug in this class
is oseltamivir (Tamiflu) has, like Relenza, been shown to
shorten the duration of flu symptoms if taken within 48 hours of
symptom onset. It is taken orally and is available in capsule form.
It is important to see your doctor at the first sign of flu symptoms
to receive effective treatment from these drugs. Studies that may
prove these medications can also prevent the onset of
influenza are currently underway.
Amantadine (Symmetrel) is one drug
that can be used for preventing the flu and is also effective in
treating Influenza Type A. Amantadine can reduce the severity and
shorten the duration of Influenza A when administered within 48
hours of symptom onset. Amantadine can be used to treat anyone over
the age of one year. Amantadine's use has been limited by its lack
of activity against influenza B, rapid emergence of resistance and
central nervous system side effects such as dizziness and confusion.
Contact Your Health Care Provider If:
- Your fever comes back after it has
been gone 1-2 days or if you still have high fever after 4 or 5
days.
- Your cough becomes wheezy or
rapid, you are having trouble breathing, or you are coughing up
bloody or yellow-green mucous.
- You have any chronic illness
(heart or lung trouble, asthma, cancer, immune system compromise,
diabetes, kidney, blood cell problems), which puts you at greater
risk for complications.
- You have any of the following:
severe confusion, seizures/convulsions, loss of consciousness,
spasms, bleeding, heart irregularity, ear pain or prolonged
headache.
Note: If you smoke, you are at
greater risk for complications and should contact your doctor if you
experience any change in your condition.
Compiled by Tom
Danforth
Armstrong Pharmacy, Armstrong, B.C.
Edited by Megan Stiles
Last Reviewed: September 2001
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